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S-allylmercapto-N-acetylcysteine ameliorates pulmonary fibrosis in mice via Nrf2 pathway activation and NF-κB, TGF-β1/Smad2/3 pathway suppression

Pulmonary fibrosis (PF) is a chronic lung disease characterised by alveolar inflammatory injury, alveolar septal thickening, and eventually fibrosis. Patients with severe Coronavirus Disease 2019 (COVID-19) may have left a certain degree of pulmonary fibrosis. PF is commonly caused by oxidative imba...

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Detalles Bibliográficos
Autores principales: Zhang, Qinxiu, Ye, Wenhui, Liu, Ying, Niu, Decao, Zhao, Xin, Li, Genjv, Qu, Ying, Zhao, Zhongxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Masson SAS. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672846/
https://www.ncbi.nlm.nih.gov/pubmed/36410121
http://dx.doi.org/10.1016/j.biopha.2022.114018