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Transgenic force sensors and software to measure force transmission across the mammalian nuclear envelope in vivo

Nuclear mechanotransduction is a growing field with exciting implications for the regulation of gene expression and cellular function. Mechanical signals may be transduced to the nuclear interior biochemically or physically through connections between the cell surface and chromatin. To define mechan...

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Detalles Bibliográficos
Autores principales: Fenelon, Kelli D., Thomas, Evan, Samani, Mohammad, Zhu, Min, Tao, Hirotaka, Sun, Yu, McNeill, Helen, Hopyan, Sevan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672859/
https://www.ncbi.nlm.nih.gov/pubmed/36350289
http://dx.doi.org/10.1242/bio.059656