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Targeted review of maximum residues levels (MRLs) for haloxyfop‐P
In compliance with Article 43 of Regulation (EC) No 396/2005, the European Food Safety Authority (EFSA) received a mandate from the European Commission to perform a targeted review of the existing maximum residues levels (MRLs) for the active substance haloxyfop‐P to check whether the existing EU MR...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672883/ https://www.ncbi.nlm.nih.gov/pubmed/36415856 http://dx.doi.org/10.2903/j.efsa.2022.7658 |
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author | Bellisai, Giulia Bernasconi, Giovanni Brancato, Alba Cabrera, Luis Carrasco Castellan, Irene Del Aguila, Monica Ferreira, Lucien Giner, German Greco, Luna Jarrah, Samira Leuschner, Renata Magrans, Jose Oriol Miron, Ileana Nave, Stefanie Pedersen, Ragnor Reich, Hermine Robinson, Tobin Ruocco, Silvia Santos, Miguel Scarlato, Alessia Pia Theobald, Anne Verani, Alessia |
author_facet | Bellisai, Giulia Bernasconi, Giovanni Brancato, Alba Cabrera, Luis Carrasco Castellan, Irene Del Aguila, Monica Ferreira, Lucien Giner, German Greco, Luna Jarrah, Samira Leuschner, Renata Magrans, Jose Oriol Miron, Ileana Nave, Stefanie Pedersen, Ragnor Reich, Hermine Robinson, Tobin Ruocco, Silvia Santos, Miguel Scarlato, Alessia Pia Theobald, Anne Verani, Alessia |
collection | PubMed |
description | In compliance with Article 43 of Regulation (EC) No 396/2005, the European Food Safety Authority (EFSA) received a mandate from the European Commission to perform a targeted review of the existing maximum residues levels (MRLs) for the active substance haloxyfop‐P to check whether the existing EU MRL in onions, sunflower seeds and soya beans (covering codex maximum residue limits (CXLs) or import tolerances) and the proposed import tolerance MRLs in linseeds, rapeseeds/canola seeds are safe for consumers and can eventually be maintained in the MRL Regulation after the expiry of the approval of the active substance. EFSA screened these MRLs considering the toxicological reference values established during the EU peer review process for the renewal of the approval of haloxyfop‐P and identified chronic consumer intake concerns for two diets when for the remaining plant and animal commodities, the input values were at the LOQ. Fall‐back MRLs could not be proposed, but the additional information provided by EURLs allowed to resolve the chronic intake concerns using lower validated LOQs for a range of plant commodities and milk. EFSA concludes that the existing EU MRLs in soya beans and onions, the CXL in sunflower seeds and the proposed import tolerances in linseed and rapeseed/canola seeds are not expected to pose a risk to consumers. However, to guarantee consumer's safety regarding the chronic exposure to haloxyfop‐P residues, the enforcement LOQs in several plant commodities and milks would have to be lowered to the levels reported by the EURLs. |
format | Online Article Text |
id | pubmed-9672883 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-96728832022-11-21 Targeted review of maximum residues levels (MRLs) for haloxyfop‐P Bellisai, Giulia Bernasconi, Giovanni Brancato, Alba Cabrera, Luis Carrasco Castellan, Irene Del Aguila, Monica Ferreira, Lucien Giner, German Greco, Luna Jarrah, Samira Leuschner, Renata Magrans, Jose Oriol Miron, Ileana Nave, Stefanie Pedersen, Ragnor Reich, Hermine Robinson, Tobin Ruocco, Silvia Santos, Miguel Scarlato, Alessia Pia Theobald, Anne Verani, Alessia EFSA J Reasoned Opinion In compliance with Article 43 of Regulation (EC) No 396/2005, the European Food Safety Authority (EFSA) received a mandate from the European Commission to perform a targeted review of the existing maximum residues levels (MRLs) for the active substance haloxyfop‐P to check whether the existing EU MRL in onions, sunflower seeds and soya beans (covering codex maximum residue limits (CXLs) or import tolerances) and the proposed import tolerance MRLs in linseeds, rapeseeds/canola seeds are safe for consumers and can eventually be maintained in the MRL Regulation after the expiry of the approval of the active substance. EFSA screened these MRLs considering the toxicological reference values established during the EU peer review process for the renewal of the approval of haloxyfop‐P and identified chronic consumer intake concerns for two diets when for the remaining plant and animal commodities, the input values were at the LOQ. Fall‐back MRLs could not be proposed, but the additional information provided by EURLs allowed to resolve the chronic intake concerns using lower validated LOQs for a range of plant commodities and milk. EFSA concludes that the existing EU MRLs in soya beans and onions, the CXL in sunflower seeds and the proposed import tolerances in linseed and rapeseed/canola seeds are not expected to pose a risk to consumers. However, to guarantee consumer's safety regarding the chronic exposure to haloxyfop‐P residues, the enforcement LOQs in several plant commodities and milks would have to be lowered to the levels reported by the EURLs. John Wiley and Sons Inc. 2022-11-18 /pmc/articles/PMC9672883/ /pubmed/36415856 http://dx.doi.org/10.2903/j.efsa.2022.7658 Text en © 2022 Wiley‐VCH Verlag GmbH & Co. KgaA on behalf of the European Food Safety Authority. https://creativecommons.org/licenses/by-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ (https://creativecommons.org/licenses/by-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made. |
spellingShingle | Reasoned Opinion Bellisai, Giulia Bernasconi, Giovanni Brancato, Alba Cabrera, Luis Carrasco Castellan, Irene Del Aguila, Monica Ferreira, Lucien Giner, German Greco, Luna Jarrah, Samira Leuschner, Renata Magrans, Jose Oriol Miron, Ileana Nave, Stefanie Pedersen, Ragnor Reich, Hermine Robinson, Tobin Ruocco, Silvia Santos, Miguel Scarlato, Alessia Pia Theobald, Anne Verani, Alessia Targeted review of maximum residues levels (MRLs) for haloxyfop‐P |
title | Targeted review of maximum residues levels (MRLs) for haloxyfop‐P
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title_full | Targeted review of maximum residues levels (MRLs) for haloxyfop‐P
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title_fullStr | Targeted review of maximum residues levels (MRLs) for haloxyfop‐P
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title_full_unstemmed | Targeted review of maximum residues levels (MRLs) for haloxyfop‐P
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title_short | Targeted review of maximum residues levels (MRLs) for haloxyfop‐P
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title_sort | targeted review of maximum residues levels (mrls) for haloxyfop‐p |
topic | Reasoned Opinion |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672883/ https://www.ncbi.nlm.nih.gov/pubmed/36415856 http://dx.doi.org/10.2903/j.efsa.2022.7658 |
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