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STAT3 is Activated by CTGF-mediated Tumor-stroma Cross Talk to Promote HCC Progression

BACKGROUND & AIMS: Signal transducer and activator of transcription 3 (STAT3) is known as a pro-oncogenic transcription factor. Regarding liver carcinogenesis, however, it remains controversial whether activated STAT3 is pro- or anti-tumorigenic. This study aimed to clarify the significance and...

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Detalles Bibliográficos
Autores principales: Makino, Yuki, Hikita, Hayato, Kato, Seiya, Sugiyama, Masaya, Shigekawa, Minoru, Sakamoto, Tatsuya, Sasaki, Yoichi, Murai, Kazuhiro, Sakane, Sadatsugu, Kodama, Takahiro, Sakamori, Ryotaro, Kobayashi, Shogo, Eguchi, Hidetoshi, Takemura, Nobuyuki, Kokudo, Norihiro, Yokoi, Hideki, Mukoyama, Masashi, Tatsumi, Tomohide, Takehara, Tetsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672888/
https://www.ncbi.nlm.nih.gov/pubmed/36210625
http://dx.doi.org/10.1016/j.jcmgh.2022.09.006