Sustainable recovery of MBNL activity in autoregulatory feedback loop in myotonic dystrophy

Muscleblind-like proteins (MBNLs) are RNA-binding proteins essential for the developmental regulation of various processes including alternative splicing. Their activity is misregulated in myotonic dystrophy type 1 (DM1), an incurable genetic, neuro-muscular disorder caused by uncontrolled expansion...

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Detalles Bibliográficos
Autores principales: Rogalska, Zuzanna, Sobczak, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672890/
https://www.ncbi.nlm.nih.gov/pubmed/36420218
http://dx.doi.org/10.1016/j.omtn.2022.10.023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672890/
https://www.ncbi.nlm.nih.gov/pubmed/36420218
http://dx.doi.org/10.1016/j.omtn.2022.10.023

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