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Selective Elimination of NRF2-Activated Cells by Competition With Neighboring Cells in the Esophageal Epithelium

BACKGROUND & AIMS: NF-E2-related factor 2 (NRF2) is a transcription factor that regulates cytoprotective gene expression in response to oxidative and electrophilic stresses. NRF2 activity is mainly controlled by Kelch-like ECH-associated protein 1 (KEAP1). Constitutive NRF2 activation by NRF2 mu...

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Detalles Bibliográficos
Autores principales: Hirose, Wataru, Horiuchi, Makoto, Li, Donghan, Motoike, Ikuko N., Zhang, Lin, Nishi, Hafumi, Taniyama, Yusuke, Kamei, Takashi, Suzuki, Mikiko, Kinoshita, Kengo, Katsuoka, Fumiki, Taguchi, Keiko, Yamamoto, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672893/
https://www.ncbi.nlm.nih.gov/pubmed/36115578
http://dx.doi.org/10.1016/j.jcmgh.2022.09.004