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Pharmacological inhibition of the acetyltransferase Tip60 mitigates myocardial infarction injury

Pharmacologic strategies that target factors with both pro-apoptotic and anti-proliferative functions in cardiomyocytes (CMs) may be useful for the treatment of ischemic heart disease. One such multifunctional candidate for drug targeting is the acetyltransferase Tip60, which is known to acetylate b...

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Detalles Bibliográficos
Autores principales: Wang, Xinrui, Wan, Tina C., Kulik, Katherine R., Lauth, Amelia, Smith, Brian C., Lough, John W., Auchampach, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672930/
https://www.ncbi.nlm.nih.gov/pubmed/36341679
http://dx.doi.org/10.1242/dmm.049786