Downregulation of protein kinase C gamma reduces epithelial property and enhances malignant phenotypes in colorectal cancer cells

Loss of epithelial integrity is associated with colorectal cancer (CRC) aggressiveness. Protein kinase C (PKC) is frequently implicated in human cancers, but the role of PKCγ in CRC remains poorly understood. Here, we show that PKCγ, a conventional PKC, is expressed in normal colonic epithelium, but...

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Detalles Bibliográficos
Autores principales: Satow, Reiko, Suzuki, Yudai, Asada, Shinobu, Ota, Sae, Idogawa, Masashi, Kubota, Shiori, Ikeo, Noi, Yoneda, Atsuko, Fukami, Kiyoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672935/
https://www.ncbi.nlm.nih.gov/pubmed/36404918
http://dx.doi.org/10.1016/j.isci.2022.105501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672935/
https://www.ncbi.nlm.nih.gov/pubmed/36404918
http://dx.doi.org/10.1016/j.isci.2022.105501

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