Cargando…

Optimization of the expression of the main protease from SARS-CoV-2

The main protease (M(pro)) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) plays a vital role in viral replication. To study the function of M(pro) and screen inhibitors targeting M(pro), it is necessary to prepare high-purity and high-activity M(pro). In this study, four types of SA...

Descripción completa

Detalles Bibliográficos
Autores principales: Rong, Yi, Zhang, Chaofeng, Gao, Wen-Chao, Zhao, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673008/
https://www.ncbi.nlm.nih.gov/pubmed/36403706
http://dx.doi.org/10.1016/j.pep.2022.106208