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Wild-type KRAS inhibits the migration and invasion of pancreatic cancer through the Wnt/β-catenin pathway

Kirsten rat sarcoma virus (KRAS) mutation is considered to be the event that leads to the initiation of pancreatic ductal adenocarcinoma (PDAC), the mutation frequency of the KRAS gene in PDAC is 90–95%. Studies have shown that wild-type KRAS (KRAS(WT)) has a survival advantage in PDAC and can antag...

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Detalles Bibliográficos
Autores principales: Hu, Xianhua, Zhang, Rendan, Yao, Jiaxin, Mu, Bo, Zhao, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673065/
https://www.ncbi.nlm.nih.gov/pubmed/36367161
http://dx.doi.org/10.3892/mmr.2022.12891