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Dexmedetomidine attenuates airway inflammation and oxidative stress in asthma via the Nrf2 signaling pathway

Allergic asthma is a chronic inflammatory disease in which oxidative stress serves a pivotal role. In clinical practice, dexmedetomidine (DEX), an α-2-adrenergic receptor agonist, is used as a sedative. DEX exhibits antioxidative and organ-protective properties. In a murine model of asthma, DEX has...

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Detalles Bibliográficos
Autores principales: Xiao, Shilin, Zhou, Ying, Gao, Huibin, Yang, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673067/
https://www.ncbi.nlm.nih.gov/pubmed/36321783
http://dx.doi.org/10.3892/mmr.2022.12889