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Anakinra or high-dose corticosteroids in COVID-19 pneumonia patients who deteriorate on low-dose dexamethasone: an observational study of comparative effectiveness

OBJECTIVES: To assess whether escalating to high-dose corticosteroids or anakinra compared with continuing low-dose corticosteroids reduced mortality in patients with severe COVID-19 whose respiratory function deteriorated while receiving dexamethasone 6 mg daily. METHODS: We conducted a retrospecti...

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Detalles Bibliográficos
Autores principales: Langer-Gould, Annette, Xu, Stanley, Myers, Laura C., Chen, Aiyu, Greene, John D., Creekmur, Beth, Bruxvoort, Katia, Adams, John L., Liu, Vincent, Gould, Michael K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673073/
https://www.ncbi.nlm.nih.gov/pubmed/36403818
http://dx.doi.org/10.1016/j.ijid.2022.11.017