Arginine ADP-Ribosylation: Chemical Synthesis of Post-Translationally Modified Ubiquitin Proteins

[Image: see text] We describe the development and optimization of a methodology to prepare peptides and proteins modified on the arginine residue with an adenosine-di-phosphate-ribosyl (ADPr) group. Our method comprises reacting an ornithine containing polypeptide on-resin with an α-linked anomeric...

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Detalles Bibliográficos
Autores principales: Voorneveld, Jim, Kloet, Max S., Wijngaarden, Sven, Kim, Robbert Q., Moutsiopoulou, Angeliki, Verdegaal, Marnix, Misra, Mohit, Đikić, Ivan, van der Marel, Gijsbert A., Overkleeft, Herman S., Filippov, Dmitri V., van der Heden van Noort, Gerbrand J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673145/
https://www.ncbi.nlm.nih.gov/pubmed/36318515
http://dx.doi.org/10.1021/jacs.2c06249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673145/
https://www.ncbi.nlm.nih.gov/pubmed/36318515
http://dx.doi.org/10.1021/jacs.2c06249

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