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Targeting TSPO Reduces Inflammation and Apoptosis in an In Vitro Photoreceptor-Like Model of Retinal Degeneration

[Image: see text] The 18 kDa translocator protein (TSPO) is predominantly located in the mitochondrial outer membrane, playing an important role in steroidogenesis, inflammation, survival, and cell proliferation. Its expression in the CNS, and mainly in glial cells, is upregulated in neuropathologie...

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Detalles Bibliográficos
Autores principales: Corsi, Francesca, Baglini, Emma, Barresi, Elisabetta, Salerno, Silvia, Cerri, Chiara, Martini, Claudia, Da Settimo Passetti, Federico, Taliani, Sabrina, Gargini, Claudia, Piano, Ilaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673150/
https://www.ncbi.nlm.nih.gov/pubmed/36300862
http://dx.doi.org/10.1021/acschemneuro.2c00582