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Targeting TSPO Reduces Inflammation and Apoptosis in an In Vitro Photoreceptor-Like Model of Retinal Degeneration
[Image: see text] The 18 kDa translocator protein (TSPO) is predominantly located in the mitochondrial outer membrane, playing an important role in steroidogenesis, inflammation, survival, and cell proliferation. Its expression in the CNS, and mainly in glial cells, is upregulated in neuropathologie...
Autores principales: | Corsi, Francesca, Baglini, Emma, Barresi, Elisabetta, Salerno, Silvia, Cerri, Chiara, Martini, Claudia, Da Settimo Passetti, Federico, Taliani, Sabrina, Gargini, Claudia, Piano, Ilaria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673150/ https://www.ncbi.nlm.nih.gov/pubmed/36300862 http://dx.doi.org/10.1021/acschemneuro.2c00582 |
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