Hemophagocytic lymphohistocytosis in trisomy 21: successful treatment with interferon inhibition

BACKGROUND: Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening condition of immune dysregulation primarily driven by the cytokine interferon gamma. It can be either a genetic or acquired disorder associated with infection, malignancy, and rheumatologic disorders. Trisomy 21 can express a...

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Detalles Bibliográficos
Autores principales: Guild, Allison, Fritch, Jordan, Patel, Sachit, Reinhardt, Adam, Acquazzino, Melissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673190/
https://www.ncbi.nlm.nih.gov/pubmed/36401314
http://dx.doi.org/10.1186/s12969-022-00764-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673190/
https://www.ncbi.nlm.nih.gov/pubmed/36401314
http://dx.doi.org/10.1186/s12969-022-00764-w

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