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Identifying hub genes of calcific aortic valve disease and revealing the immune infiltration landscape based on multiple WGCNA and single-cell sequence analysis

BACKGROUND: Calcific aortic valve disease (CAVD) is a progressive fibrocalcific disease that can be treated only through valve replacement. This study aimed to determine the role of hub genes and immune cell infiltration in CAVD progression. METHODS: In this study, bioinformatics analysis was used t...

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Detalles Bibliográficos
Autores principales: Wang, Kan, Zheng, Qiang, Liu, Xing, Geng, BingChuan, Dong, NianGuo, Shi, JiaWei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673246/
https://www.ncbi.nlm.nih.gov/pubmed/36405745
http://dx.doi.org/10.3389/fimmu.2022.1035285