N6-methyladenosine-mediated SH3BP5-AS1 upregulation promotes GEM chemoresistance in pancreatic cancer by activating the Wnt signaling pathway

BACKGROUND: Pancreatic cancer (PC) is highly malignant. Chemotherapy is the main treatment strategy, especially for patients with advanced PC. However, chemoresistance has always been a frequently encountered bottleneck. Hence, there is an urgent need to enhance the sensitivity of PC to gemcitabine...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Chengjie, Wang, Yan, Dong, Yihong, Lai, Shihui, Wang, Liang, Weng, Shangeng, Zhang, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673340/
https://www.ncbi.nlm.nih.gov/pubmed/36397058
http://dx.doi.org/10.1186/s13062-022-00347-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673340/
https://www.ncbi.nlm.nih.gov/pubmed/36397058
http://dx.doi.org/10.1186/s13062-022-00347-5

Ejemplares similares