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N6-methyladenosine-mediated SH3BP5-AS1 upregulation promotes GEM chemoresistance in pancreatic cancer by activating the Wnt signaling pathway

BACKGROUND: Pancreatic cancer (PC) is highly malignant. Chemotherapy is the main treatment strategy, especially for patients with advanced PC. However, chemoresistance has always been a frequently encountered bottleneck. Hence, there is an urgent need to enhance the sensitivity of PC to gemcitabine...

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Detalles Bibliográficos
Autores principales:	Lin, Chengjie, Wang, Yan, Dong, Yihong, Lai, Shihui, Wang, Liang, Weng, Shangeng, Zhang, Xiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673340/ https://www.ncbi.nlm.nih.gov/pubmed/36397058 http://dx.doi.org/10.1186/s13062-022-00347-5

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