HNRNPA2B1-mediated m6A modification of TLR4 mRNA promotes progression of multiple myeloma

BACKGROUND: Multiple myeloma (MM) is a malignancy of plasma cells that remains incurable. Toll-like receptor 4 (TLR4) acts as a stress-responsive signal, protecting mitochondria during proteasome inhibitor (PI) exposure, maintaining mitochondrial metabolism and increasing drug resistance in MM. Howe...

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Detalles Bibliográficos
Autores principales: Quan, Lina, Jia, Chuiming, Guo, Yiwei, Chen, Yao, Wang, Xinya, Xu, Qiuting, Zhang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673362/
https://www.ncbi.nlm.nih.gov/pubmed/36401285
http://dx.doi.org/10.1186/s12967-022-03750-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673362/
https://www.ncbi.nlm.nih.gov/pubmed/36401285
http://dx.doi.org/10.1186/s12967-022-03750-8

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