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HNRNPA2B1-mediated m6A modification of TLR4 mRNA promotes progression of multiple myeloma

BACKGROUND: Multiple myeloma (MM) is a malignancy of plasma cells that remains incurable. Toll-like receptor 4 (TLR4) acts as a stress-responsive signal, protecting mitochondria during proteasome inhibitor (PI) exposure, maintaining mitochondrial metabolism and increasing drug resistance in MM. Howe...

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Detalles Bibliográficos
Autores principales:	Quan, Lina, Jia, Chuiming, Guo, Yiwei, Chen, Yao, Wang, Xinya, Xu, Qiuting, Zhang, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673362/ https://www.ncbi.nlm.nih.gov/pubmed/36401285 http://dx.doi.org/10.1186/s12967-022-03750-8

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