Cargando…

HNRNPA2B1-mediated m6A modification of TLR4 mRNA promotes progression of multiple myeloma

BACKGROUND: Multiple myeloma (MM) is a malignancy of plasma cells that remains incurable. Toll-like receptor 4 (TLR4) acts as a stress-responsive signal, protecting mitochondria during proteasome inhibitor (PI) exposure, maintaining mitochondrial metabolism and increasing drug resistance in MM. Howe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Quan, Lina, Jia, Chuiming, Guo, Yiwei, Chen, Yao, Wang, Xinya, Xu, Qiuting, Zhang, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673362/ https://www.ncbi.nlm.nih.gov/pubmed/36401285 http://dx.doi.org/10.1186/s12967-022-03750-8

Ejemplares similares

Correction: HNRNPA2B1-mediated m6A modification of TLR4 mRNA promotes progression of multiple myeloma
por: Jia, Chuiming, et al.
Publicado: (2023)

HNRNPA2B1 promotes multiple myeloma progression by increasing AKT3 expression via m6A-dependent stabilization of ILF3 mRNA
por: Jiang, Fengjie, et al.
Publicado: (2021)

m(6)A reader hnRNPA2B1 drives multiple myeloma osteolytic bone disease
por: Liu, Rui, et al.
Publicado: (2022)

Identification of an mRNA isoform switch for HNRNPA1 in breast cancers
por: Erdem, Murat, et al.
Publicado: (2021)

hnRNPA2B1 promotes the occurrence and progression of hepatocellular carcinoma by downregulating PCK1 mRNA via a m6A RNA methylation manner
por: Hao, Weijie, et al.
Publicado: (2023)

ALKBH5 Promotes Multiple Myeloma Tumorigenicity through inducing m(6)A-demethylation of SAV1 mRNA and Myeloma Stem Cell Phenotype
por: Yu, Tingting, et al.
Publicado: (2022)

Interaction of lncRNA MIR100HG with hnRNPA2B1 facilitates m(6)A-dependent stabilization of TCF7L2 mRNA and colorectal cancer progression
por: Liu, Hao, et al.
Publicado: (2022)

Dynamic regulation and functions of mRNA m6A modification
por: Wang, Shanshan, et al.
Publicado: (2022)

Modulation of translational decoding by m(6)A modification of mRNA
por: Jain, Sakshi, et al.
Publicado: (2023)

Analysis of mRNA m(6)A modification and mRNA expression profiles in middle ear cholesteatoma
por: Xie, Shumin, et al.
Publicado: (2023)

m(6)A Reader HNRNPA2B1 Promotes Esophageal Cancer Progression via Up-Regulation of ACLY and ACC1
por: Guo, Huimin, et al.
Publicado: (2020)

Aberrant Regulation of mRNA m(6)A Modification in Cancer Development
por: Luo, Junyun, et al.
Publicado: (2018)

Diverse molecular functions of m(6)A mRNA modification in cancer
por: Han, Seung Hun, et al.
Publicado: (2020)

N(6)-methyladenosine modification of ITGA6 mRNA promotes the development and progression of bladder cancer
por: Jin, Huan, et al.
Publicado: (2019)

METTL3 Contributes to Osteosarcoma Progression by Increasing DANCR mRNA Stability via m6A Modification
por: Zhou, Xinying, et al.
Publicado: (2022)

FTO‐mediated m(6)A modification of SOCS1 mRNA promotes the progression of diabetic kidney disease
por: Sun, Qiang, et al.
Publicado: (2022)

The Significance of mRNA in the Biology of Multiple Myeloma and Its Clinical Implications
por: Puła, Anna, et al.
Publicado: (2021)

New mRNA modification?
por: Leslie, Mitch
Publicado: (2007)

Dynamic m(6)A modification regulates local translation of mRNA in axons
por: Yu, Jun, et al.
Publicado: (2018)

Limited effects of m(6)A modification on mRNA partitioning into stress granules
por: Khong, Anthony, et al.
Publicado: (2022)

miR-128 Restriction of LINE-1 (L1) Retrotransposition Is Dependent on Targeting hnRNPA1 mRNA
por: Fung, Lianna, et al.
Publicado: (2019)

HNRNPA2B1, as a m(6)A Reader, Promotes Tumorigenesis and Metastasis of Oral Squamous Cell Carcinoma
por: Zhu, Feiya, et al.
Publicado: (2021)

Corrigendum: METTL3 contributes to osteosarcoma progression by increasing DANCR mRNA stability via m6A modification
por: Zhou, Xinying, et al.
Publicado: (2023)

m(6)A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover
por: Ke, Shengdong, et al.
Publicado: (2017)

Advances in mRNA 5-methylcytosine modifications: Detection, effectors, biological functions, and clinical relevance
por: Guo, Gangqiang, et al.
Publicado: (2021)

Response to COVID-19 mRNA vaccination in multiple myeloma is conserved but impaired compared to controls
por: Bitoun, Samuel, et al.
Publicado: (2021)

Response to mRNA vaccination for COVID-19 among patients with multiple myeloma
por: Stampfer, Samuel D., et al.
Publicado: (2021)

Third dose of an mRNA COVID-19 vaccine for patients with multiple myeloma
por: Goldwater, Marissa-Skye, et al.
Publicado: (2023)

Coordinate regulation of alternative pre-mRNA splicing events by the human RNA chaperone proteins hnRNPA1 and DDX5
por: Lee, Yeon J., et al.
Publicado: (2018)

METTL3-mediated m6A modification of SIRT1 mRNA inhibits progression of endometriosis by cellular senescence enhancing
por: Wang, Xiaotong, et al.
Publicado: (2023)

Methyltransferase-like 14 silencing relieves the development of atherosclerosis via m(6)A modification of p65 mRNA
por: Liu, Yingjie, et al.
Publicado: (2022)

N(6)-Methyladenosine mRNA Modification: From Modification Site Selectivity to Neurological Functions
por: Zhang, Zeyu, et al.
Publicado: (2023)

A fly view on the roles and mechanisms of the m(6)A mRNA modification and its players
por: Lence, Tina, et al.
Publicado: (2017)

Reading and writing of mRNA m(6)A modification orchestrate maternal-to-zygotic transition in mice
por: Zhu, Wencheng, et al.
Publicado: (2023)

METTL3-mediated m(6)A mRNA modification promotes esophageal cancer initiation and progression via Notch signaling pathway
por: Han, Hui, et al.
Publicado: (2021)

METTL3-mediated m6A modification of Bcl-2 mRNA promotes non-small cell lung cancer progression
por: Zhang, Yongxi, et al.
Publicado: (2021)

Activation of the HNRNPA2B1/miR-93-5p/FRMD6 axis facilitates prostate cancer progression in an m6A-dependent manner
por: Sun, Menghao, et al.
Publicado: (2023)

Compensatory expression regulation of highly homologous proteins HNRNPA1 and HNRNPA2
por: CHANG, Yan, et al.
Publicado: (2021)

Multiple Sclerosis-Associated hnRNPA1 Mutations Alter hnRNPA1 Dynamics and Influence Stress Granule Formation
por: Clarke, Joseph-Patrick W. E., et al.
Publicado: (2021)

Identification and Validation of Three m6A Regulators: FTO, HNRNPC, and HNRNPA2B1 as Potential Biomarkers for Endometriosis
por: Sun, Jiani, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_1v2vnoh89p3ea2al3c2m54i04k