A single-cell human islet interactome atlas identifies disrupted autocrine and paracrine communications in type 2 diabetes

A sensible control of hormone secretion from pancreatic islets requires concerted inter-cellular communications, but a comprehensive picture of the whole islet interactome is presently missing. Single-cell transcriptomics allows to overcome this and we used here a single-cell dataset from type 2 dia...

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Detalles Bibliográficos
Autores principales: Bosi, Emanuele, Marselli, Lorella, Suleiman, Mara, Tesi, Marta, De Luca, Carmela, Del Guerra, Silvia, Cnop, Miriam, Eizirik, Decio L, Marchetti, Piero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Standard Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673496/
https://www.ncbi.nlm.nih.gov/pubmed/36415826
http://dx.doi.org/10.1093/nargab/lqac084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673496/
https://www.ncbi.nlm.nih.gov/pubmed/36415826
http://dx.doi.org/10.1093/nargab/lqac084

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