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A single-cell human islet interactome atlas identifies disrupted autocrine and paracrine communications in type 2 diabetes
A sensible control of hormone secretion from pancreatic islets requires concerted inter-cellular communications, but a comprehensive picture of the whole islet interactome is presently missing. Single-cell transcriptomics allows to overcome this and we used here a single-cell dataset from type 2 dia...
Autores principales: | Bosi, Emanuele, Marselli, Lorella, Suleiman, Mara, Tesi, Marta, De Luca, Carmela, Del Guerra, Silvia, Cnop, Miriam, Eizirik, Decio L, Marchetti, Piero |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673496/ https://www.ncbi.nlm.nih.gov/pubmed/36415826 http://dx.doi.org/10.1093/nargab/lqac084 |
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