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Defining the characteristics of interferon-alpha–stimulated human genes: insight from expression data and machine learning

BACKGROUND: A virus-infected cell triggers a signalling cascade, resulting in the secretion of interferons (IFNs), which in turn induces the upregulation of the IFN-stimulated genes (ISGs) that play a role in antipathogen host defence. Here, we conducted analyses on large-scale data relating to evol...

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Detalles Bibliográficos
Autores principales: Chai, Haiting, Gu, Quan, Robertson, David L, Hughes, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673497/
https://www.ncbi.nlm.nih.gov/pubmed/36399061
http://dx.doi.org/10.1093/gigascience/giac103