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Defining the characteristics of interferon-alpha–stimulated human genes: insight from expression data and machine learning
BACKGROUND: A virus-infected cell triggers a signalling cascade, resulting in the secretion of interferons (IFNs), which in turn induces the upregulation of the IFN-stimulated genes (ISGs) that play a role in antipathogen host defence. Here, we conducted analyses on large-scale data relating to evol...
Autores principales: | Chai, Haiting, Gu, Quan, Robertson, David L, Hughes, Joseph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673497/ https://www.ncbi.nlm.nih.gov/pubmed/36399061 http://dx.doi.org/10.1093/gigascience/giac103 |
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