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Function and Constraint in Enhancer Sequences with Multiple Evolutionary Origins
Thousands of human gene regulatory enhancers are composed of sequences with multiple evolutionary origins. These evolutionarily “complex” enhancers consist of older “core” sequences and younger “derived” sequences. However, the functional relationship between the sequences of different evolutionary...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673499/ https://www.ncbi.nlm.nih.gov/pubmed/36314566 http://dx.doi.org/10.1093/gbe/evac159 |