Loss of Rbl2 (Retinoblastoma‐Like 2) Exacerbates Myocardial Ischemia/Reperfusion Injury

BACKGROUND: The postmitotic state of adult cardiomyocytes, maintained by the cell cycle repressor Rbl2 (retinoblastoma‐like 2), is associated with considerable resistance to apoptosis. However, whether Rbl2 regulates cardiomyocyte apoptosis remains unknown. METHODS AND RESULTS: Here, we show that ab...

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Detalles Bibliográficos
Autores principales: Chen, Jingrui, Xia, Peng, Liu, Yuening, Kogan, Clark, Cheng, Zhaokang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673695/
https://www.ncbi.nlm.nih.gov/pubmed/36129061
http://dx.doi.org/10.1161/JAHA.121.024764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673695/
https://www.ncbi.nlm.nih.gov/pubmed/36129061
http://dx.doi.org/10.1161/JAHA.121.024764

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