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Loss of Rbl2 (Retinoblastoma‐Like 2) Exacerbates Myocardial Ischemia/Reperfusion Injury
BACKGROUND: The postmitotic state of adult cardiomyocytes, maintained by the cell cycle repressor Rbl2 (retinoblastoma‐like 2), is associated with considerable resistance to apoptosis. However, whether Rbl2 regulates cardiomyocyte apoptosis remains unknown. METHODS AND RESULTS: Here, we show that ab...
Autores principales: | Chen, Jingrui, Xia, Peng, Liu, Yuening, Kogan, Clark, Cheng, Zhaokang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673695/ https://www.ncbi.nlm.nih.gov/pubmed/36129061 http://dx.doi.org/10.1161/JAHA.121.024764 |
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