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Cell‐Specific Actions of the Prostaglandin E‐Prostanoid Receptor 4 Attenuating Hypertension: A Dominant Role for Kidney Epithelial Cells Compared With Macrophages

BACKGROUND: A beneficial role for prostanoids in hypertension is suggested by clinical studies showing nonsteroidal anti‐inflammatory drugs, which block the production of all prostanoids, cause sodium retention and exacerbate hypertension. Among prostanoids, prostaglandin E2 and its E‐prostanoid rec...

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Detalles Bibliográficos
Autores principales: Yang, Ting, Song, Chengcheng, Ralph, Donna L., Andrews, Portia, Sparks, Matthew A., Koller, Beverly H., McDonough, Alicia A., Coffman, Thomas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673718/
https://www.ncbi.nlm.nih.gov/pubmed/36172956
http://dx.doi.org/10.1161/JAHA.122.026581