Protein Kinase D1 Regulates Cardiac Hypertrophy, Potassium Channel Remodeling, and Arrhythmias in Heart Failure

BACKGROUND: Structural and electrophysiological remodeling characterize heart failure (HF) enhancing arrhythmias. PKD1 (protein kinase D1) is upregulated in HF and mediates pathological hypertrophic signaling, but its role in K+ channel remodeling and arrhythmogenesis in HF is unknown. METHODS AND R...

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Detalles Bibliográficos
Autores principales: Bossuyt, Julie, Borst, Johanna M., Verberckmoes, Marie, Bailey, Logan R. J., Bers, Donald M., Hegyi, Bence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673734/
https://www.ncbi.nlm.nih.gov/pubmed/36172952
http://dx.doi.org/10.1161/JAHA.122.027573

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673734/
https://www.ncbi.nlm.nih.gov/pubmed/36172952
http://dx.doi.org/10.1161/JAHA.122.027573

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