Cargando…

Protein Kinase D1 Regulates Cardiac Hypertrophy, Potassium Channel Remodeling, and Arrhythmias in Heart Failure

BACKGROUND: Structural and electrophysiological remodeling characterize heart failure (HF) enhancing arrhythmias. PKD1 (protein kinase D1) is upregulated in HF and mediates pathological hypertrophic signaling, but its role in K+ channel remodeling and arrhythmogenesis in HF is unknown. METHODS AND R...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bossuyt, Julie, Borst, Johanna M., Verberckmoes, Marie, Bailey, Logan R. J., Bers, Donald M., Hegyi, Bence
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673734/ https://www.ncbi.nlm.nih.gov/pubmed/36172952 http://dx.doi.org/10.1161/JAHA.122.027573

Ejemplares similares

Diabetes and Excess Aldosterone Promote Heart Failure With Preserved Ejection Fraction
por: Hegyi, Bence, et al.
Publicado: (2022)

Up‐regulation of miR‐195 contributes to cardiac hypertrophy‐induced arrhythmia by targeting calcium and potassium channels
por: Xuan, Lina, et al.
Publicado: (2020)

Cardiomyocyte Na(+) and Ca(2+) mishandling drives vicious cycle involving CaMKII, ROS, and ryanodine receptors
por: Hegyi, Bence, et al.
Publicado: (2021)

Voltage Dependent Potassium Channel Remodeling in Murine Intestinal Smooth Muscle Hypertrophy Induced by Partial Obstruction
por: Liu, Dong-Hai, et al.
Publicado: (2014)

Remodeling of Ion Channel Trafficking and Cardiac Arrhythmias
por: Blandin, Camille E., et al.
Publicado: (2021)

Nuclear CaMKII enhances histone H3 phosphorylation and remodels chromatin during cardiac hypertrophy
por: Awad, Salma, et al.
Publicado: (2013)

Circadian Mechanisms: Cardiac Ion Channel Remodeling and Arrhythmias
por: Bernardi, Joyce, et al.
Publicado: (2021)

Bone marrow mesenchymal stem cells protected post-infarcted myocardium against arrhythmias via reversing potassium channels remodelling
por: Cai, Benzhi, et al.
Publicado: (2014)

Atrial Arrhythmias, Digitalis and Potassium
por: Goodyer, Allan V. N.
Publicado: (1959)

Mechanoelectric coupling and arrhythmogenesis in cardiomyocytes contracting under mechanical afterload in a 3D viscoelastic hydrogel
por: Hegyi, Bence, et al.
Publicado: (2021)

Bromide of Potassium in Hypertrophy of the Spleen
Publicado: (1875)

Caveolin-3 Microdomain: Arrhythmia Implications for Potassium Inward Rectifier and Cardiac Sodium Channel
por: Vaidyanathan, Ravi, et al.
Publicado: (2018)

Multistep Ion Channel Remodeling and Lethal Arrhythmia Precede Heart Failure in a Mouse Model of Inherited Dilated Cardiomyopathy
por: Suzuki, Takeshi, et al.
Publicado: (2012)

Hypertrophic cardiomyopathy with little hypertrophy and severe arrhythmia
por: Ripoll-Vera, Tomas, et al.
Publicado: (2018)

CaMKII Serine 280 O-GlcNAcylation Links Diabetic Hyperglycemia to Proarrhythmia
por: Hegyi, Bence, et al.
Publicado: (2021)

Sodium leak through K2P potassium channels and cardiac arrhythmia, an emerging theme
por: Goldstein, Steve AN
Publicado: (2017)

ATP-Sensitive Potassium Channel Currents in Eccentrically Hypertrophied Cardiac Myocytes of Volume-Overloaded Rats
por: Alvin, Zikiar V., et al.
Publicado: (2011)

Angiotensin II Receptor Blockers and Arrhythmias in Ventricular Hypertrophy
por: Salama, Guy
Publicado: (2022)

Kv1.1 potassium channel subunit deficiency alters ventricular arrhythmia susceptibility, contractility, and repolarization
por: Trosclair, Krystle, et al.
Publicado: (2021)

Pioglitazone Improves Potassium Channel Remodeling Induced by Angiotensin II in Atrial Myocytes
por: Gu, Jun, et al.
Publicado: (2014)

I(K1) Channel Agonist Zacopride Alleviates Cardiac Hypertrophy and Failure via Alterations in Calcium Dyshomeostasis and Electrical Remodeling in Rats
por: Liu, Qing-Hua, et al.
Publicado: (2019)

The Mechanism of High-Output Cardiac Hypertrophy Arising From Potassium Channel Gain-of-Function in Cantú Syndrome
por: McClenaghan, Conor, et al.
Publicado: (2020)

When Is a Potassium Channel Not a Potassium Channel?
por: Accili, Eric
Publicado: (2022)

Effects of Wenxin Keli on Cardiac Hypertrophy and Arrhythmia via Regulation of the Calcium/Calmodulin Dependent Kinase II Signaling Pathway
por: Yang, Xinyu, et al.
Publicado: (2017)

Trigger-Specific Remodeling of K(Ca)2 Potassium Channels in Models of Atrial Fibrillation
por: Rahm, Ann-Kathrin, et al.
Publicado: (2021)

Modulation of the Kv1.3 Potassium Channel by Receptor Tyrosine Kinases
por: Bowlby, Mark R., et al.
Publicado: (1997)

Regulation of Kv1.4 potassium channels by PKC and AMPK kinases
por: Andersen, Martin Nybo, et al.
Publicado: (2017)

Basal Septal Hypertrophy as the Early Imaging Biomarker for Adaptive Phase of Remodeling Prior to Heart Failure
por: Yalçin, Fatih, et al.
Publicado: (2021)

Remodeling of Arterial Tone Regulation in Postnatal Development: Focus on Smooth Muscle Cell Potassium Channels
por: Shvetsova, Anastasia A., et al.
Publicado: (2021)

Allisartan ameliorates vascular remodeling through regulation of voltage-gated potassium channels in hypertensive rats
por: Zhang, Xiaoqin, et al.
Publicado: (2021)

Functional remodelling of perinuclear mitochondria alters nucleoplasmic Ca(2+) signalling in heart failure
por: Voglhuber, Julia, et al.
Publicado: (2022)

Role of CyPA in cardiac hypertrophy and remodeling
por: Cao, Mengfei, et al.
Publicado: (2019)

Structure of potassium channels
por: Kuang, Qie, et al.
Publicado: (2015)

Regulation of the instantaneous inward rectifier and the delayed outward rectifier potassium channels by Captopril and Angiotensin II via the Phosphoinositide-3 kinase pathway in volume-overload-induced hypertrophied cardiac myocytes
por: Alvin, Zikiar, et al.
Publicado: (2011)

Inhibition of Angiotensin II-Induced Cardiac Hypertrophy and Associated Ventricular Arrhythmias by a p21 Activated Kinase 1 Bioactive Peptide
por: Wang, Rui, et al.
Publicado: (2014)

Is hypertensive left ventricular hypertrophy a cause of sustained ventricular arrhythmias in humans?
por: Nadarajah, R., et al.
Publicado: (2021)

Arrhythmia related to hypertensive left ventricular hypertrophy in Iraqi patients: frequency and outcome
por: Al Alwany, Ameen Abdulhasan
Publicado: (2022)

Intermolecular Failure of L-type Ca(2+) Channel and Ryanodine Receptor Signaling in Hypertrophy
por: Xu, Ming, et al.
Publicado: (2007)

CaMKIIδC Drives Early Adaptive Ca(2+) Change and Late Eccentric Cardiac Hypertrophy
por: Ljubojevic-Holzer, Senka, et al.
Publicado: (2020)

Nuclear Translocation of Cardiac G Protein-Coupled Receptor Kinase 5 Downstream of Select Gq-Activating Hypertrophic Ligands Is a Calmodulin-Dependent Process
por: Gold, Jessica I., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_f7tjmmb7sqn35a3bcm5u8bm3ro