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Sodium Tanshinone IIA Sulfonate Inhibits Vascular Endothelial Cell Pyroptosis via the AMPK Signaling Pathway in Atherosclerosis

INTRODUCTION: Atherosclerosis (AS) is the underlying cause of cardiovascular events. Endothelial cell mitochondrial damage and pyroptosis are important factors contributing to AS. Changes in internal mitochondrial conformation and increase in reactive oxygen species (ROS) lead to the disruption of m...

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Detalles Bibliográficos
Autores principales: Zhu, Ji, Chen, Hang, Guo, Jianan, Zha, Chen, Lu, Dezhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673812/
https://www.ncbi.nlm.nih.gov/pubmed/36408328
http://dx.doi.org/10.2147/JIR.S386470