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Diminished neutralization responses towards SARS-CoV-2 Omicron VoC after mRNA or vector-based COVID-19 vaccinations

SARS-CoV-2 variants accumulating immune escape mutations provide a significant risk to vaccine-induced protection against infection. The novel variant of concern (VoC) Omicron BA.1 and its sub-lineages have the largest number of amino acid alterations in its Spike protein to date. Thus, they may eff...

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Detalles Bibliográficos
Autores principales: Jacobsen, Henning, Strengert, Monika, Maaß, Henrike, Ynga Durand, Mario Alberto, Katzmarzyk, Maeva, Kessel, Barbora, Harries, Manuela, Rand, Ulfert, Abassi, Leila, Kim, Yeonsu, Lüddecke, Tatjana, Metzdorf, Kristin, Hernandez, Pilar, Ortmann, Julia, Heise, Jana-Kristin, Castell, Stefanie, Gornyk, Daniela, Glöckner, Stephan, Melhorn, Vanessa, Kemmling, Yvonne, Lange, Berit, Dulovic, Alex, Marsall, Patrick, Häring, Julia, Junker, Daniel, Schneiderhan-Marra, Nicole, Hoffmann, Markus, Pöhlmann, Stefan, Krause, Gérard, Cicin-Sain, Luka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673895/
https://www.ncbi.nlm.nih.gov/pubmed/36400804
http://dx.doi.org/10.1038/s41598-022-22552-y