High-Throughput Assay for Identifying Diverse Antagonists of the Binding Interaction between the ACE2 Receptor and the Dynamic Spike Proteins of SARS-CoV-2

[Image: see text] SARS-CoV-2, a coronavirus strain that started a worldwide pandemic in early 2020, attaches to human cells by binding its spike (S) glycoprotein to a host receptor protein angiotensin-converting enzyme 2 (ACE2). Blocking the interaction between the S protein and ACE2 has emerged as...

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Detalles Bibliográficos
Autores principales: Sammons, Rachel M., Bohanon, Amanda L., Kowtha, Anvith, Dejong, Audrey, Cho, Eun Jeong, Kaoud, Tamer S., Dalby, Kevin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673917/
https://www.ncbi.nlm.nih.gov/pubmed/36315931
http://dx.doi.org/10.1021/acsinfecdis.2c00297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673917/
https://www.ncbi.nlm.nih.gov/pubmed/36315931
http://dx.doi.org/10.1021/acsinfecdis.2c00297

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