Single-molecule imaging reveals how mavacamten and PKA modulate ATP turnover in skeletal muscle myofibrils

Muscle contraction is controlled at two levels: the thin and the thick filaments. The latter level of control involves three states of myosin heads: active, disordered relaxed (DRX), and super-relaxed (SRX), the distribution of which controls the number of myosins available to interact with actin. H...

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Detalles Bibliográficos
Autores principales: Pilagov, Matvey, Heling, Laurens W.H.J., Walklate, Jonathan, Geeves, Michael A., Kad, Neil M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674027/
https://www.ncbi.nlm.nih.gov/pubmed/36394553
http://dx.doi.org/10.1085/jgp.202213087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674027/
https://www.ncbi.nlm.nih.gov/pubmed/36394553
http://dx.doi.org/10.1085/jgp.202213087

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