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cAMP-PKA signaling modulates the automaticity of human iPSC-derived cardiomyocytes

Human-induced pluripotent stem cell–derived cardiomyocytes (hiPSC-CMs) have been used to screen and characterize drugs and to reveal mechanisms underlying cardiac diseases. However, before hiPSC-CMs can be used as a reliable experimental model, the physiological mechanisms underlying their normal fu...

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Detalles Bibliográficos
Autores principales: Mazgaoker, Savyon, Weiser-Bitoun, Ido, Brosh, Inbar, Binah, Ofer, Yaniv, Yael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674091/
https://www.ncbi.nlm.nih.gov/pubmed/36383232
http://dx.doi.org/10.1085/jgp.202213153