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Cannabinoids activate the insulin pathway to modulate mobilization of cholesterol in C. elegans

The nematode Caenorhabditis elegans requires exogenous cholesterol to survive and its depletion leads to early developmental arrest. Thus, tight regulation of cholesterol storage and distribution within the organism is critical. Previously, we demonstrated that the endocannabinoid (eCB) 2-arachidono...

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Detalles Bibliográficos
Autores principales: Hernandez-Cravero, Bruno, Gallino, Sofia, Florman, Jeremy, Vranych, Cecilia, Diaz, Philippe, Elgoyhen, Ana Belén, Alkema, Mark J., de Mendoza, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674138/
https://www.ncbi.nlm.nih.gov/pubmed/36346800
http://dx.doi.org/10.1371/journal.pgen.1010346