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Network topology metrics explaining enrichment of hybrid epithelial/mesenchymal phenotypes in metastasis

Epithelial to Mesenchymal Transition (EMT) and its reverse—Mesenchymal to Epithelial Transition (MET) are hallmarks of metastasis. Cancer cells use this reversible cellular programming to switch among Epithelial (E), Mesenchymal (M), and hybrid Epithelial/Mesenchymal (hybrid E/M) state(s) and seed t...

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Detalles Bibliográficos
Autores principales: Rashid, Mubasher, Hari, Kishore, Thampi, John, Santhosh, Nived Krishnan, Jolly, Mohit Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674141/
https://www.ncbi.nlm.nih.gov/pubmed/36346808
http://dx.doi.org/10.1371/journal.pcbi.1010687