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Leveraging a natural murine meiotic drive to suppress invasive populations

Invasive rodents are a major cause of environmental damage and biodiversity loss, particularly on islands. Unlike insects, genetic biocontrol strategies including population-suppressing gene drives with biased inheritance have not been developed in mice. Here, we demonstrate a gene drive strategy (t...

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Detalles Bibliográficos
Autores principales: Gierus, Luke, Birand, Aysegul, Bunting, Mark D., Godahewa, Gelshan I., Piltz, Sandra G., Oh, Kevin P., Piaggio, Antoinette J., Threadgill, David W., Godwin, John, Edwards, Owain, Cassey, Phillip, Ross, Joshua V., Prowse, Thomas A. A., Thomas, Paul Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674240/
https://www.ncbi.nlm.nih.gov/pubmed/36346842
http://dx.doi.org/10.1073/pnas.2213308119