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Phloretin enhances remyelination by stimulating oligodendrocyte precursor cell differentiation

Failure of remyelination underlies the progressive nature of demyelinating diseases such as multiple sclerosis. Why endogenous repair mechanisms frequently fail in these disorders is poorly understood. However, there is now evidence indicating that this is related to an overly inflammatory microenvi...

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Detalles Bibliográficos
Autores principales: Dierckx, Tess, Vanherle, Sam, Haidar, Mansour, Grajchen, Elien, Mingneau, Fleur, Gervois, Pascal, Wolfs, Esther, Bylemans, Dany, Voet, Arnout, Nguyen, Tien, Hamad, Ibrahim, Kleinewietfeld, Markus, Bogie, Jeroen F. J., Hendriks, Jerome J. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674257/
https://www.ncbi.nlm.nih.gov/pubmed/36343243
http://dx.doi.org/10.1073/pnas.2120393119