Cargando…
Phloretin enhances remyelination by stimulating oligodendrocyte precursor cell differentiation
Failure of remyelination underlies the progressive nature of demyelinating diseases such as multiple sclerosis. Why endogenous repair mechanisms frequently fail in these disorders is poorly understood. However, there is now evidence indicating that this is related to an overly inflammatory microenvi...
Autores principales: | Dierckx, Tess, Vanherle, Sam, Haidar, Mansour, Grajchen, Elien, Mingneau, Fleur, Gervois, Pascal, Wolfs, Esther, Bylemans, Dany, Voet, Arnout, Nguyen, Tien, Hamad, Ibrahim, Kleinewietfeld, Markus, Bogie, Jeroen F. J., Hendriks, Jerome J. A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674257/ https://www.ncbi.nlm.nih.gov/pubmed/36343243 http://dx.doi.org/10.1073/pnas.2120393119 |
Ejemplares similares
-
Phloretin suppresses neuroinflammation by autophagy-mediated Nrf2 activation in macrophages
por: Dierckx, Tess, et al.
Publicado: (2021) -
Stearoyl-CoA desaturase-1 impairs the reparative properties of macrophages and microglia in the brain
por: Bogie, Jeroen F.J., et al.
Publicado: (2020) -
Altered PPARγ Expression Promotes Myelin-Induced Foam Cell Formation in Macrophages in Multiple Sclerosis
por: Wouters, Elien, et al.
Publicado: (2020) -
CD36-mediated uptake of myelin debris by macrophages and microglia reduces neuroinflammation
por: Grajchen, Elien, et al.
Publicado: (2020) -
The physiology of foamy phagocytes in multiple sclerosis
por: Grajchen, Elien, et al.
Publicado: (2018)