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SMC protein RecN drives RecA filament translocation for in vivo homology search

While the molecular repertoire of the homologous recombination pathways is well studied, the search mechanism that enables recombination between distant homologous regions is poorly understood. Earlier work suggests that the recombinase RecA, an essential component for homology search, forms an elon...

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Detalles Bibliográficos
Autores principales: Chimthanawala, Afroze, Parmar, Jyotsana J., Kumar, Sujan, Iyer, Krishnan S., Rao, Madan, Badrinarayanan, Anjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674259/
https://www.ncbi.nlm.nih.gov/pubmed/36346847
http://dx.doi.org/10.1073/pnas.2209304119