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Letting go: Dishevelled phase separation recruits Axin to stabilize β-catenin
Dishevelled exerts a molecular force that guides cell fate, but how it does so remains enigmatic. In this issue, Kang et al. (2022. J. Cell Biol. https://doi.org/10.1083/jcb.202205069) show Dvl2 undergoes liquid–liquid phase separation to stabilize β-catenin by pulling Axin into its biomolecular con...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Rockefeller University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674272/ https://www.ncbi.nlm.nih.gov/pubmed/36383195 http://dx.doi.org/10.1083/jcb.202211001 |