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Spatially targeted brain cancer immunotherapy with closed-loop controlled focused ultrasound and immune checkpoint blockade

Despite the challenges in treating glioblastomas (GBMs) with immune adjuvants, increasing evidence suggests that targeting the immune cells within the tumor microenvironment (TME) can lead to improved responses. Here, we present a closed-loop controlled, microbubble-enhanced focused ultrasound (MB-F...

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Detalles Bibliográficos
Autores principales: Lee, Hohyun, Guo, Yutong, Ross, James L., Schoen, Scott, Degertekin, F. Levent, Arvanitis, Costas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674274/
https://www.ncbi.nlm.nih.gov/pubmed/36399574
http://dx.doi.org/10.1126/sciadv.add2288