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Diabetic hyperglycemia promotes primary tumor progression through glycation-induced tumor extracellular matrix stiffening

Diabetes mellitus is a complex metabolic disorder that is associated with an increased risk of breast cancer. Despite this correlation, the interplay between tumor progression and diabetes, particularly with regard to stiffening of the extracellular matrix, is still mechanistically unclear. Here, we...

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Detalles Bibliográficos
Autores principales: Wang, Wenjun, Hapach, Lauren A., Griggs, Lauren, Smart, Kyra, Wu, Yusheng, Taufalele, Paul V., Rowe, Matthew M., Young, Katherine M., Bates, Madison E., Johnson, Andrew C., Ferrell, Nicholas J., Pozzi, Ambra, Reinhart-King, Cynthia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674287/
https://www.ncbi.nlm.nih.gov/pubmed/36399580
http://dx.doi.org/10.1126/sciadv.abo1673