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Diabetic hyperglycemia promotes primary tumor progression through glycation-induced tumor extracellular matrix stiffening
Diabetes mellitus is a complex metabolic disorder that is associated with an increased risk of breast cancer. Despite this correlation, the interplay between tumor progression and diabetes, particularly with regard to stiffening of the extracellular matrix, is still mechanistically unclear. Here, we...
Autores principales: | Wang, Wenjun, Hapach, Lauren A., Griggs, Lauren, Smart, Kyra, Wu, Yusheng, Taufalele, Paul V., Rowe, Matthew M., Young, Katherine M., Bates, Madison E., Johnson, Andrew C., Ferrell, Nicholas J., Pozzi, Ambra, Reinhart-King, Cynthia A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674287/ https://www.ncbi.nlm.nih.gov/pubmed/36399580 http://dx.doi.org/10.1126/sciadv.abo1673 |
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