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Pointed-end processive elongation of actin filaments by Vibrio effectors VopF and VopL

According to the cellular actin dynamics paradigm, filaments grow at their barbed ends and depolymerize predominantly from their pointed ends to form polar structures and do productive work. We show that actin can elongate at the pointed end when assisted by Vibrio VopF/L toxins, which act as proces...

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Detalles Bibliográficos
Autores principales: Kudryashova, Elena, Ankita, Ulrichs, Heidi, Shekhar, Shashank, Kudryashov, Dmitri S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674292/
https://www.ncbi.nlm.nih.gov/pubmed/36399577
http://dx.doi.org/10.1126/sciadv.adc9239