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Mettl3-mediated m(6)A modification of Fgf16 restricts cardiomyocyte proliferation during heart regeneration
Cardiovascular disease is the leading cause of death worldwide due to the inability of adult heart to regenerate after injury. N(6)-methyladenosine (m(6)A) methylation catalyzed by the enzyme methyltransferase-like 3 (Mettl3) plays an important role in various physiological and pathological bioproce...
Autores principales: | Jiang, Fu-Qing, Liu, Kun, Chen, Jia-Xuan, Cao, Yan, Chen, Wu-Yun, Zhao, Wan-Ling, Song, Guo-Hua, Liang, Chi-Qian, Zhou, Yi-Min, Huang, Huan-Lei, Huang, Rui-Jin, Zhao, Hui, Park, Kyu-Sang, Ju, Zhenyu, Cai, Dongqing, Qi, Xu-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674341/ https://www.ncbi.nlm.nih.gov/pubmed/36399125 http://dx.doi.org/10.7554/eLife.77014 |
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