Alternative splicing downstream of EMT enhances phenotypic plasticity and malignant behavior in colon cancer

Phenotypic plasticity allows carcinoma cells to transiently acquire the quasi-mesenchymal features necessary to detach from the primary mass and proceed along the invasion-metastasis cascade. A broad spectrum of epigenetic mechanisms is likely to cause the epithelial-to-mesenchymal (EMT) and mesench...

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Detalles Bibliográficos
Autores principales: Xu, Tong, Verhagen, Mathijs, Joosten, Rosalie, Sun, Wenjie, Sacchetti, Andrea, Munoz Sagredo, Leonel, Orian-Rousseau, Véronique, Fodde, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674345/
https://www.ncbi.nlm.nih.gov/pubmed/36346211
http://dx.doi.org/10.7554/eLife.82006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674345/
https://www.ncbi.nlm.nih.gov/pubmed/36346211
http://dx.doi.org/10.7554/eLife.82006

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