T cell deficiency precipitates antibody evasion and emergence of neurovirulent polyomavirus

JC polyomavirus (JCPyV) causes progressive multifocal leukoencephalopathy (PML), a life-threatening brain disease in immunocompromised patients. Inherited and acquired T cell deficiencies are associated with PML. The incidence of PML is increasing with the introduction of new immunomodulatory agents...

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Detalles Bibliográficos
Autores principales: Lauver, Matthew D, Jin, Ge, Ayers, Katelyn N, Carey, Sarah N, Specht, Charles S, Abendroth, Catherine S, Lukacher, Aron E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Microbiology and Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674346/
https://www.ncbi.nlm.nih.gov/pubmed/36341713
http://dx.doi.org/10.7554/eLife.83030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674346/
https://www.ncbi.nlm.nih.gov/pubmed/36341713
http://dx.doi.org/10.7554/eLife.83030

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